siRNA, Anti-PGK1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16340WQ-2OMe)

The product SIRGT16340WQ-2OMe is a type of small interfering RNA (siRNA) that targets PGK1 gene and regulates the expression of gene. The siRNA interferes with the expression of PGK1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000291.3
Alternative Names HEL-S-68p; MIG10; PGKA
Related Diseases Phosphoglycerate Kinase 1 Deficiency
Purification HPLC
Target Gene
Gene ID 5230
Uniprot ID P00558
Sub Cat Target Species Modification Scale  
SIRGT17340WQ-2F PGK1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18340WQ-2MOE PGK1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19340WQ-LNA PGK1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16340WQ-RB PGK1 Human Ribo-modified Inquiry
SIRGT17340WQ-BB PGK1 Human Backbone-modified Inquiry

Related Products