siRNA, Anti-PGRMC2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31798WQ-2OMe)

The product SIRGT31798WQ-2OMe is a type of small interfering RNA (siRNA) that targets PGRMC2 gene and regulates the expression of gene. The siRNA interferes with the expression of PGRMC2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006320.4
Alternative Names DG6; PMBP
Related Diseases Achalasia-Addisonianism-Alacrima Syndrome
Purification HPLC
Target Gene
Gene ID 10424
Uniprot ID O15173
Sub Cat Target Species Modification Scale  
SIRGT32798WQ-2F PGRMC2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33798WQ-2MOE PGRMC2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34798WQ-LNA PGRMC2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31798WQ-RB PGRMC2 Human Ribo-modified Inquiry
SIRGT32798WQ-BB PGRMC2 Human Backbone-modified Inquiry

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