siRNA, Anti-PKD2L1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT26730WQ-2OMe)

The product SIRGT26730WQ-2OMe is a type of small interfering RNA (siRNA) that targets PKD2L1 gene and regulates the expression of gene. The siRNA interferes with the expression of PKD2L1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001253837.1; NM_016112.2
Alternative Names PCL; PKD2L; PKDL; TRPP3
Related Diseases Polycystic Kidney Disease
Purification HPLC
Target Gene
Gene ID 9033
Uniprot ID Q9P0L9
Sub Cat Target Species Modification Scale  
SIRGT27730WQ-2F PKD2L1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28730WQ-2MOE PKD2L1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT26730WQ-RB PKD2L1 Human Ribo-modified Inquiry
SIRGT27730WQ-BB PKD2L1 Human Backbone-modified Inquiry

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