siRNA, Anti-PKDREJ, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31741WQ-2OMe)

The product SIRGT31741WQ-2OMe is a type of small interfering RNA (siRNA) that targets PKDREJ gene and regulates the expression of gene. The siRNA interferes with the expression of PKDREJ gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006071.1
Related Diseases Polycystic Kidney Disease
Purification HPLC
Target Gene
Gene ID 10343
Uniprot ID Q9NTG1
Sub Cat Target Species Modification Scale  
SIRGT32741WQ-2F PKDREJ Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33741WQ-2MOE PKDREJ Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34741WQ-LNA PKDREJ Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31741WQ-RB PKDREJ Human Ribo-modified Inquiry
SIRGT32741WQ-BB PKDREJ Human Backbone-modified Inquiry

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