siRNA, Anti-PKLR, Ribo-modified(CAT#: SIRGT16398WQ-RB)
The product SIRGT16398WQ-RB is a type of small interfering RNA (siRNA) that targets PKLR gene and regulates the expression of gene. The siRNA interferes with the expression of PKLR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with Ribo modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | Ribo-modified |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_000298.5; NM_181871.3 |
| Alternative Names | PK1; PKL; PKR; PKRL; RPK |
| Related Diseases | Chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA) |
| Purification | HPLC |