siRNA, Anti-PKNOX1, LNA/Ribo/Backbone-modified(CAT#: SIRGT19401WQ-LNA)

The product SIRGT19401WQ-LNA is a type of small interfering RNA (siRNA) that targets PKNOX1 gene and regulates the expression of gene. The siRNA interferes with the expression of PKNOX1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001286258.1; NM_001320694.1; NM_004571.4
Alternative Names PREP1; pkonx1c
Related Diseases Down Syndrome
Purification HPLC
Target Gene
Gene ID 5316
Uniprot ID P55347
Sub Cat Target Species Modification Scale  
SIRGT16401WQ-RB PKNOX1 Human Ribo-modified Inquiry
SIRGT17401WQ-BB PKNOX1 Human Backbone-modified Inquiry

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