siRNA, Anti-PLOD2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16432WQ-2OMe)

The product SIRGT16432WQ-2OMe is a type of small interfering RNA (siRNA) that targets PLOD2 gene and regulates the expression of gene. The siRNA interferes with the expression of PLOD2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000935.2; NM_182943.2
Alternative Names BRKS2; LH2; TLH
Related Diseases Bruck syndrome
Purification HPLC
Target Gene
Gene ID 5352
Uniprot ID O00469
Sub Cat Target Species Modification Scale  
SIRGT17432WQ-2F PLOD2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18432WQ-2MOE PLOD2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19432WQ-LNA PLOD2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16432WQ-RB PLOD2 Human Ribo-modified Inquiry
SIRGT17432WQ-BB PLOD2 Human Backbone-modified Inquiry

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