siRNA, Anti-PNP, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16083WQ-2OMe)

The product SIRGT16083WQ-2OMe is a type of small interfering RNA (siRNA) that targets PNP gene and regulates the expression of gene. The siRNA interferes with the expression of PNP gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000270.3
Alternative Names NP; PRO1837; PUNP
Related Diseases Purine Nucleoside Phosphorylase Deficiency
Purification HPLC
Target Gene
Gene ID 4860
Uniprot ID P00491
Sub Cat Target Species Modification Scale  
SIRGT17083WQ-2F PNP Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18083WQ-2MOE PNP Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19083WQ-LNA PNP Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16083WQ-RB PNP Human Ribo-modified Inquiry
SIRGT17083WQ-BB PNP Human Backbone-modified Inquiry

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