siRNA, Anti-POF1B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46354WQ-2OMe)

The product SIRGT46354WQ-2OMe is a type of small interfering RNA (siRNA) that targets POF1B gene and regulates the expression of gene. The siRNA interferes with the expression of POF1B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001307940.1
Alternative Names POF; POF2B
Related Diseases Premature Ovarian Failure 2B
Purification HPLC
Target Gene
Gene ID 79983
Uniprot ID Q8WVV4
Sub Cat Target Species Modification Scale  
SIRGT47354WQ-2F POF1B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48354WQ-2MOE POF1B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49354WQ-LNA POF1B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46354WQ-RB POF1B Human Ribo-modified Inquiry
SIRGT47354WQ-BB POF1B Human Backbone-modified Inquiry

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