siRNA, Anti-POLRMT, 2'-F-modified(CAT#: SIRGT17486WQ-2F)

The product SIRGT17486WQ-2F is a type of small interfering RNA (siRNA) that targets POLRMT gene and regulates the expression of gene. The siRNA interferes with the expression of POLRMT gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2ʹ-deoxy-2ʹ-fluoro (2'-F)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_005035.3
Alternative Names APOLMT; MTRNAP; MTRPOL; h-mtRPOL
Related Diseases Leber Optic Atrophy
Purification HPLC
Target Gene
Gene ID 5442
Uniprot ID O00411

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