siRNA, Anti-PPFIA4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26349WQ-2OMe)

The product SIRGT26349WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPFIA4 gene and regulates the expression of gene. The siRNA interferes with the expression of PPFIA4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001304331.1; NM_001304332.1
Related Diseases Dandy-Walker Syndrome
Purification HPLC
Target Gene
Gene ID 8497
Uniprot ID O75335
Sub Cat Target Species Modification Scale  
SIRGT27349WQ-2F PPFIA4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28349WQ-2MOE PPFIA4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29349WQ-LNA PPFIA4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26349WQ-RB PPFIA4 Human Ribo-modified Inquiry
SIRGT27349WQ-BB PPFIA4 Human Backbone-modified Inquiry

Related Products