siRNA, Anti-PPP1CA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16524WQ-2OMe)
The product SIRGT16524WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPP1CA gene and regulates the expression of gene. The siRNA interferes with the expression of PPP1CA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001008709.1; NM_002708.3; NM_206873.1 |
| Alternative Names | PP-1A; PP1A; PP1alpha; PPP1A |
| Related Diseases | Venezuelan Equine Encephalitis |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT17524WQ-2F | PPP1CA | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT18524WQ-2MOE | PPP1CA | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT19524WQ-LNA | PPP1CA | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT16524WQ-RB | PPP1CA | Human | Ribo-modified | ||
| SIRGT17524WQ-BB | PPP1CA | Human | Backbone-modified |
