siRNA, Anti-PPP1CC, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT16526WQ-2OMe)

The product SIRGT16526WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPP1CC gene and regulates the expression of gene. The siRNA interferes with the expression of PPP1CC gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001244974.1; NM_002710.3
Alternative Names PP-1G; PP1C; PPP1G
Related Diseases Rheumatoid Arthritis
Purification HPLC
Target Gene
Gene ID 5501
Uniprot ID P36873
Sub Cat Target Species Modification Scale  
SIRGT17526WQ-2F PPP1CC Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18526WQ-2MOE PPP1CC Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT16526WQ-RB PPP1CC Human Ribo-modified Inquiry
SIRGT17526WQ-BB PPP1CC Human Backbone-modified Inquiry

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