siRNA, Anti-PPP1R15A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41099WQ-2OMe)

The product SIRGT41099WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPP1R15A gene and regulates the expression of gene. The siRNA interferes with the expression of PPP1R15A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_014330.3
Alternative Names GADD34
Related Diseases Malignant Pleural Mesothelioma
Purification HPLC
Target Gene
Gene ID 23645
Uniprot ID O75807
Sub Cat Target Species Modification Scale  
SIRGT42099WQ-2F PPP1R15A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43099WQ-2MOE PPP1R15A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44099WQ-LNA PPP1R15A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41099WQ-RB PPP1R15A Human Ribo-modified Inquiry
SIRGT42099WQ-BB PPP1R15A Human Backbone-modified Inquiry

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