siRNA, Anti-PPP1R17, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36103WQ-2OMe)

The product SIRGT36103WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPP1R17 gene and regulates the expression of gene. The siRNA interferes with the expression of PPP1R17 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001145123.2; NM_006658.4
Alternative Names C7orf16; GSBS
Related Diseases Hypercholesterolemia, Familial, 1
Purification HPLC
Target Gene
Gene ID 10842
Uniprot ID O96001
Sub Cat Target Species Modification Scale  
SIRGT37103WQ-2F PPP1R17 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38103WQ-2MOE PPP1R17 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39103WQ-LNA PPP1R17 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36103WQ-RB PPP1R17 Human Ribo-modified Inquiry
SIRGT37103WQ-BB PPP1R17 Human Backbone-modified Inquiry

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