siRNA, Anti-PPP1R1B, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT46801WQ-2OMe)

The product SIRGT46801WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPP1R1B gene and regulates the expression of gene. The siRNA interferes with the expression of PPP1R1B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001242464.1
Alternative Names DARPP-32; DARPP32
Related Diseases Heart Disease and Schizophrenia
Purification HPLC
Target Gene
Gene ID 84152
Uniprot ID Q9UD71
Sub Cat Target Species Modification Scale  
SIRGT47801WQ-2F PPP1R1B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT49801WQ-LNA PPP1R1B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46801WQ-RB PPP1R1B Human Ribo-modified Inquiry
SIRGT47801WQ-BB PPP1R1B Human Backbone-modified Inquiry

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