siRNA, Anti-PPP2R1A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16537WQ-2OMe)

The product SIRGT16537WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPP2R1A gene and regulates the expression of gene. The siRNA interferes with the expression of PPP2R1A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_014225.5
Alternative Names MRD36; PP2A-Aalpha; PP2AA; PP2AAALPHA; PR65A
Related Diseases Pervasive Developmental Disorder
Purification HPLC
Target Gene
Gene ID 5518
Uniprot ID P30153
Sub Cat Target Species Modification Scale  
SIRGT17537WQ-2F PPP2R1A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18537WQ-2MOE PPP2R1A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19537WQ-LNA PPP2R1A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16537WQ-RB PPP2R1A Human Ribo-modified Inquiry
SIRGT17537WQ-BB PPP2R1A Human Backbone-modified Inquiry

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