siRNA, Anti-PSENEN, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41965WQ-2OMe)

The product SIRGT41965WQ-2OMe is a type of small interfering RNA (siRNA) that targets PSENEN gene and regulates the expression of gene. The siRNA interferes with the expression of PSENEN gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001281532.2
Alternative Names MDS033; MSTP064; PEN-2; PEN2
Related Diseases Dowling-Degos Disease
Purification HPLC
Target Gene
Gene ID 55851
Uniprot ID Q9NZ42
Sub Cat Target Species Modification Scale  
SIRGT42965WQ-2F PSENEN Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43965WQ-2MOE PSENEN Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44965WQ-LNA PSENEN Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41965WQ-RB PSENEN Human Ribo-modified Inquiry
SIRGT42965WQ-BB PSENEN Human Backbone-modified Inquiry

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