siRNA, Anti-PTGFR, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16716WQ-2OMe)

The product SIRGT16716WQ-2OMe is a type of small interfering RNA (siRNA) that targets PTGFR gene and regulates the expression of gene. The siRNA interferes with the expression of PTGFR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000959.3; NM_001039585.1
Alternative Names FP
Related Diseases Ocular Hyperemia, Ocular Hypertension
Purification HPLC
Target Gene
Gene ID 5737
Uniprot ID P43088
Sub Cat Target Species Modification Scale  
SIRGT17716WQ-2F PTGFR Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18716WQ-2MOE PTGFR Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19716WQ-LNA PTGFR Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16716WQ-RB PTGFR Human Ribo-modified Inquiry
SIRGT17716WQ-BB PTGFR Human Backbone-modified Inquiry

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