siRNA, Anti-PTGIS, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16719WQ-2OMe)

The product SIRGT16719WQ-2OMe is a type of small interfering RNA (siRNA) that targets PTGIS gene and regulates the expression of gene. The siRNA interferes with the expression of PTGIS gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000961.3
Alternative Names CYP8; CYP8A1; PGIS; PTGI
Related Diseases Pulmonary Hypertension
Purification HPLC
Target Gene
Gene ID 5740
Uniprot ID Q16647
Sub Cat Target Species Modification Scale  
SIRGT17719WQ-2F PTGIS Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18719WQ-2MOE PTGIS Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19719WQ-LNA PTGIS Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16719WQ-RB PTGIS Human Ribo-modified Inquiry
SIRGT17719WQ-BB PTGIS Human Backbone-modified Inquiry

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