siRNA, Anti-RAB39A, LNA/Ribo/Backbone-modified(CAT#: SIRGT44254WQ-LNA)
The product SIRGT44254WQ-LNA is a type of small interfering RNA (siRNA) that targets RAB39A gene and regulates the expression of gene. The siRNA interferes with the expression of RAB39A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_017516.2 |
| Alternative Names | RAB39 |
| Related Diseases | Autosomal Dominant Non-Syndromic Intellectual Disability |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT41254WQ-RB | RAB39A | Human | Ribo-modified | ||
| SIRGT42254WQ-BB | RAB39A | Human | Backbone-modified |