siRNA, Anti-RAB5A, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16791WQ-2OMe)

The product SIRGT16791WQ-2OMe is a type of small interfering RNA (siRNA) that targets RAB5A gene and regulates the expression of gene. The siRNA interferes with the expression of RAB5A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001292048.1; NM_004162.4
Alternative Names RAB5
Related Diseases Choroideremia, Motor Neuron Disease
Purification HPLC
Target Gene
Gene ID 5868
Uniprot ID P20339
Sub Cat Target Species Modification Scale  
SIRGT18791WQ-2MOE RAB5A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19791WQ-LNA RAB5A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16791WQ-RB RAB5A Human Ribo-modified Inquiry
SIRGT17791WQ-BB RAB5A Human Backbone-modified Inquiry

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