siRNA, Anti-RAB5B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16792WQ-2OMe)

The product SIRGT16792WQ-2OMe is a type of small interfering RNA (siRNA) that targets RAB5B gene and regulates the expression of gene. The siRNA interferes with the expression of RAB5B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001252036.1; NM_001252037.1; NM_002868.3
Related Diseases Metabolism of proteins
Purification HPLC
Target Gene
Gene ID 5869
Uniprot ID P61020
Sub Cat Target Species Modification Scale  
SIRGT17792WQ-2F RAB5B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18792WQ-2MOE RAB5B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19792WQ-LNA RAB5B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16792WQ-RB RAB5B Human Ribo-modified Inquiry
SIRGT17792WQ-BB RAB5B Human Backbone-modified Inquiry

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