siRNA, Anti-RHOBTB1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31374WQ-2OMe)
The product SIRGT31374WQ-2OMe is a type of small interfering RNA (siRNA) that targets RHOBTB1 gene and regulates the expression of gene. The siRNA interferes with the expression of RHOBTB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001242359.1; NM_001350902.1; NM_001350903.1; NM_001350904.1; NM_001350905.1; NM_001350906.1; NM_001350907.1; NM_001350908.1; NM_001350909.1; NM_001350910.1; NM_001350911.1; NM_014836.4 |
| Related Diseases | Ascaridiasis, Toxic Megacolon |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT32374WQ-2F | RHOBTB1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT33374WQ-2MOE | RHOBTB1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT34374WQ-LNA | RHOBTB1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT31374WQ-RB | RHOBTB1 | Human | Ribo-modified | ||
| SIRGT32374WQ-BB | RHOBTB1 | Human | Backbone-modified |
