siRNA, Anti-RNF113A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26032WQ-2OMe)

The product SIRGT26032WQ-2OMe is a type of small interfering RNA (siRNA) that targets RNF113A gene and regulates the expression of gene. The siRNA interferes with the expression of RNF113A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006978.2
Alternative Names Cwc24; RNF113; TTD5; ZNF183
Related Diseases Trichothiodystrophy 5, Nonphotosensitive
Purification HPLC
Target Gene
Gene ID 7737
Uniprot ID O15541
Sub Cat Target Species Modification Scale  
SIRGT27032WQ-2F RNF113A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28032WQ-2MOE RNF113A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29032WQ-LNA RNF113A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26032WQ-RB RNF113A Human Ribo-modified Inquiry
SIRGT27032WQ-BB RNF113A Human Backbone-modified Inquiry

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