siRNA, Anti-RPIA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36580WQ-2OMe)

The product SIRGT36580WQ-2OMe is a type of small interfering RNA (siRNA) that targets RPIA gene and regulates the expression of gene. The siRNA interferes with the expression of RPIA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_144563.2
Alternative Names RPI; RPIAD
Related Diseases Ribose 5-Phosphate Isomerase Deficiency
Purification HPLC
Target Gene
Gene ID 22934
Uniprot ID P49247
Sub Cat Target Species Modification Scale  
SIRGT37580WQ-2F RPIA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38580WQ-2MOE RPIA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39580WQ-LNA RPIA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36580WQ-RB RPIA Human Ribo-modified Inquiry
SIRGT37580WQ-BB RPIA Human Backbone-modified Inquiry

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