siRNA, Anti-RRAGB, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT34730WQ-LNA)

The product SIRGT34730WQ-LNA is a type of small interfering RNA (siRNA) that targets RRAGB gene and regulates the expression of gene. The siRNA interferes with the expression of RRAGB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001354011.1; NM_001354013.1; NM_006064.4; NM_016656.3
Alternative Names RAGB; bA465E19.1
Related Diseases Polycystic Echinococcosis
Purification HPLC
Target Gene
Gene ID 10325
Uniprot ID Q5VZM2
Sub Cat Target Species Modification Scale  
SIRGT101403WQ-2OMe Rragb Mouse 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT102403WQ-2F Rragb Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT103403WQ-2MOE Rragb Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT104403WQ-LNA Rragb Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT31730WQ-RB RRAGB Human Ribo-modified Inquiry
SIRGT32730WQ-BB RRAGB Human Backbone-modified Inquiry
SIRGT102403WQ-BB Rragb Mouse Backbone-modified Inquiry

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