siRNA, Anti-S100A11, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21057WQ-2OMe)

The product SIRGT21057WQ-2OMe is a type of small interfering RNA (siRNA) that targets S100A11 gene and regulates the expression of gene. The siRNA interferes with the expression of S100A11 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005620.1
Alternative Names HEL-S-43; MLN70; S100C
Related Diseases Dry Eye Syndrome
Purification HPLC
Target Gene
Gene ID 6282
Uniprot ID P31949
Sub Cat Target Species Modification Scale  
SIRGT22057WQ-2F S100A11 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23057WQ-2MOE S100A11 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24057WQ-LNA S100A11 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21057WQ-RB S100A11 Human Ribo-modified Inquiry
SIRGT22057WQ-BB S100A11 Human Backbone-modified Inquiry

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