siRNA, Anti-SELENOW, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21151WQ-2OMe)

The product SIRGT21151WQ-2OMe is a type of small interfering RNA (siRNA) that targets SELENOW gene and regulates the expression of gene. The siRNA interferes with the expression of SELENOW gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003009.3
Alternative Names SEPW1; selW
Related Diseases Keshan Disease
Purification HPLC
Target Gene
Gene ID 6415
Uniprot ID P63302
Sub Cat Target Species Modification Scale  
SIRGT22151WQ-2F SELENOW Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23151WQ-2MOE SELENOW Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24151WQ-LNA SELENOW Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21151WQ-RB SELENOW Human Ribo-modified Inquiry
SIRGT22151WQ-BB SELENOW Human Backbone-modified Inquiry

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