siRNA, Anti-SEMA3E, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31234WQ-2OMe)

The product SIRGT31234WQ-2OMe is a type of small interfering RNA (siRNA) that targets SEMA3E gene and regulates the expression of gene. The siRNA interferes with the expression of SEMA3E gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001178129.1; NM_012431.2
Alternative Names M-SEMAH; M-SemaK; SEMAH; coll-5
Related Diseases Charge Syndrome
Purification HPLC
Target Gene
Gene ID 9723
Uniprot ID O15041
Sub Cat Target Species Modification Scale  
SIRGT33234WQ-2MOE SEMA3E Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34234WQ-LNA SEMA3E Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31234WQ-RB SEMA3E Human Ribo-modified Inquiry
SIRGT32234WQ-BB SEMA3E Human Backbone-modified Inquiry

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