siRNA, Anti-SEMA5B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41150WQ-2OMe)

The product SIRGT41150WQ-2OMe is a type of small interfering RNA (siRNA) that targets SEMA5B gene and regulates the expression of gene. The siRNA interferes with the expression of SEMA5B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001031702.3
Alternative Names SEMAG; SemG
Related Diseases Diffuse Glomerulonephritis
Purification HPLC
Target Gene
Gene ID 54437
Uniprot ID Q9P283
Sub Cat Target Species Modification Scale  
SIRGT42150WQ-2F SEMA5B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43150WQ-2MOE SEMA5B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44150WQ-LNA SEMA5B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41150WQ-RB SEMA5B Human Ribo-modified Inquiry
SIRGT42150WQ-BB SEMA5B Human Backbone-modified Inquiry

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