siRNA, Anti-SFRP5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21159WQ-2OMe)

The product SIRGT21159WQ-2OMe is a type of small interfering RNA (siRNA) that targets SFRP5 gene and regulates the expression of gene. The siRNA interferes with the expression of SFRP5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003015.3
Alternative Names SARP3
Related Diseases Ovarian Clear Cell Adenocarcinoma
Purification HPLC
Target Gene
Gene ID 6425
Uniprot ID Q5T4F7
Sub Cat Target Species Modification Scale  
SIRGT22159WQ-2F SFRP5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23159WQ-2MOE SFRP5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24159WQ-LNA SFRP5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21159WQ-RB SFRP5 Human Ribo-modified Inquiry
SIRGT22159WQ-BB SFRP5 Human Backbone-modified Inquiry

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