siRNA, Anti-SGSH, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT21178WQ-2OMe)

The product SIRGT21178WQ-2OMe is a type of small interfering RNA (siRNA) that targets SGSH gene and regulates the expression of gene. The siRNA interferes with the expression of SGSH gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000199.4; NM_001352921.1; NM_001352922.1
Alternative Names HSS; MPS3A; SFMD
Related Diseases Sanfilippo syndrome A
Purification HPLC
Target Gene
Gene ID 6448
Uniprot ID P51688
Sub Cat Target Species Modification Scale  
SIRGT22178WQ-2F SGSH Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT24178WQ-LNA SGSH Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21178WQ-RB SGSH Human Ribo-modified Inquiry
SIRGT22178WQ-BB SGSH Human Backbone-modified Inquiry

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