siRNA, Anti-SGTA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21179WQ-2OMe)

The product SIRGT21179WQ-2OMe is a type of small interfering RNA (siRNA) that targets SGTA gene and regulates the expression of gene. The siRNA interferes with the expression of SGTA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003021.3
Alternative Names SGT; alphaSGT; hSGT
Related Diseases Central Nervous System Rhabdomyosarcoma
Purification HPLC
Target Gene
Gene ID 6449
Uniprot ID O43765
Sub Cat Target Species Modification Scale  
SIRGT22179WQ-2F SGTA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23179WQ-2MOE SGTA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24179WQ-LNA SGTA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21179WQ-RB SGTA Human Ribo-modified Inquiry
SIRGT22179WQ-BB SGTA Human Backbone-modified Inquiry

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