siRNA, Anti-SH2B2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31942WQ-2OMe)

The product SIRGT31942WQ-2OMe is a type of small interfering RNA (siRNA) that targets SH2B2 gene and regulates the expression of gene. The siRNA interferes with the expression of SH2B2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_020979.4
Alternative Names APS
Related Diseases Development EPO-induced Jak-STAT pathway
Purification HPLC
Target Gene
Gene ID 10603
Uniprot ID O14492
Sub Cat Target Species Modification Scale  
SIRGT32942WQ-2F SH2B2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33942WQ-2MOE SH2B2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34942WQ-LNA SH2B2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31942WQ-RB SH2B2 Human Ribo-modified Inquiry
SIRGT32942WQ-BB SH2B2 Human Backbone-modified Inquiry

Related Products