siRNA, Anti-SHPK, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41121WQ-2OMe)

The product SIRGT41121WQ-2OMe is a type of small interfering RNA (siRNA) that targets SHPK gene and regulates the expression of gene. The siRNA interferes with the expression of SHPK gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_013276.2
Alternative Names CARKL; SHK
Related Diseases Sedoheptulokinase Deficiency and Cystinosis
Purification HPLC
Target Gene
Gene ID 23729
Uniprot ID Q9UHJ6
Sub Cat Target Species Modification Scale  
SIRGT42121WQ-2F SHPK Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43121WQ-2MOE SHPK Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44121WQ-LNA SHPK Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41121WQ-RB SHPK Human Ribo-modified Inquiry
SIRGT42121WQ-BB SHPK Human Backbone-modified Inquiry

Related Products