siRNA, Anti-SIAH1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21196WQ-2OMe)

The product SIRGT21196WQ-2OMe is a type of small interfering RNA (siRNA) that targets SIAH1 gene and regulates the expression of gene. The siRNA interferes with the expression of SIAH1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001006610.1; NM_003031.3
Alternative Names SIAH1A
Related Diseases Parkinson Disease, Late-Onset
Purification HPLC
Target Gene
Gene ID 6477
Uniprot ID Q8IUQ4
Sub Cat Target Species Modification Scale  
SIRGT22196WQ-2F SIAH1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23196WQ-2MOE SIAH1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24196WQ-LNA SIAH1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21196WQ-RB SIAH1 Human Ribo-modified Inquiry
SIRGT22196WQ-BB SIAH1 Human Backbone-modified Inquiry

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