siRNA, Anti-SIAH2, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT21197WQ-2OMe)

The product SIRGT21197WQ-2OMe is a type of small interfering RNA (siRNA) that targets SIAH2 gene and regulates the expression of gene. The siRNA interferes with the expression of SIAH2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005067.5
Alternative Names hSiah2
Related Diseases Usher Syndrome
Purification HPLC
Target Gene
Gene ID 6478
Uniprot ID O43255
Sub Cat Target Species Modification Scale  
SIRGT22197WQ-2F SIAH2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT24197WQ-LNA SIAH2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21197WQ-RB SIAH2 Human Ribo-modified Inquiry
SIRGT22197WQ-BB SIAH2 Human Backbone-modified Inquiry

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