siRNA, Anti-SIX3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21210WQ-2OMe)

The product SIRGT21210WQ-2OMe is a type of small interfering RNA (siRNA) that targets SIX3 gene and regulates the expression of gene. The siRNA interferes with the expression of SIX3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005413.3
Alternative Names HPE2
Related Diseases Schizencephaly, Holoprosencephaly 2
Purification HPLC
Target Gene
Gene ID 6496
Uniprot ID O95343
Sub Cat Target Species Modification Scale  
SIRGT22210WQ-2F SIX3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23210WQ-2MOE SIX3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24210WQ-LNA SIX3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21210WQ-RB SIX3 Human Ribo-modified Inquiry
SIRGT22210WQ-BB SIX3 Human Backbone-modified Inquiry

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