siRNA, Anti-SIX6, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16158WQ-2OMe)

The product SIRGT16158WQ-2OMe is a type of small interfering RNA (siRNA) that targets SIX6 gene and regulates the expression of gene. The siRNA interferes with the expression of SIX6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_007374.2
Alternative Names MCOPCT2; ODRMD; OPTX2; Six9
Related Diseases Macular Dystrophy, Microphthalmia
Purification HPLC
Target Gene
Gene ID 4990
Uniprot ID O95475
Sub Cat Target Species Modification Scale  
SIRGT17158WQ-2F SIX6 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18158WQ-2MOE SIX6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19158WQ-LNA SIX6 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16158WQ-RB SIX6 Human Ribo-modified Inquiry
SIRGT17158WQ-BB SIX6 Human Backbone-modified Inquiry

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