siRNA, Anti-SKI, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21211WQ-2OMe)

The product SIRGT21211WQ-2OMe is a type of small interfering RNA (siRNA) that targets SKI gene and regulates the expression of gene. The siRNA interferes with the expression of SKI gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003036.3
Alternative Names SGS; SKV
Related Diseases Chromosome 1P36 Deletion Syndrome
Purification HPLC
Target Gene
Gene ID 6497
Uniprot ID P12755
Sub Cat Target Species Modification Scale  
SIRGT22211WQ-2F SKI Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23211WQ-2MOE SKI Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24211WQ-LNA SKI Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21211WQ-RB SKI Human Ribo-modified Inquiry
SIRGT22211WQ-BB SKI Human Backbone-modified Inquiry

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