siRNA, Anti-SLC10A2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21263WQ-2OMe)

The product SIRGT21263WQ-2OMe is a type of small interfering RNA (siRNA) that targets SLC10A2 gene and regulates the expression of gene. The siRNA interferes with the expression of SLC10A2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000452.2
Alternative Names ASBT; IBAT; ISBT; NTCP2; PBAM
Related Diseases Familial hypertriglyceridemia (FHTG)
Purification HPLC
Target Gene
Gene ID 6555
Uniprot ID Q12908
Sub Cat Target Species Modification Scale  
SIRGT22263WQ-2F SLC10A2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23263WQ-2MOE SLC10A2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24263WQ-LNA SLC10A2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21263WQ-RB SLC10A2 Human Ribo-modified Inquiry
SIRGT22263WQ-BB SLC10A2 Human Backbone-modified Inquiry

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