siRNA, Anti-SLC11A1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21264WQ-2OMe)

The product SIRGT21264WQ-2OMe is a type of small interfering RNA (siRNA) that targets SLC11A1 gene and regulates the expression of gene. The siRNA interferes with the expression of SLC11A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000578.3
Alternative Names LSH; NRAMP; NRAMP1
Related Diseases Buruli Ulcer, Typhoid Fever
Purification HPLC
Target Gene
Gene ID 6556
Uniprot ID P49279
Sub Cat Target Species Modification Scale  
SIRGT22264WQ-2F SLC11A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23264WQ-2MOE SLC11A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24264WQ-LNA SLC11A1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21264WQ-RB SLC11A1 Human Ribo-modified Inquiry
SIRGT22264WQ-BB SLC11A1 Human Backbone-modified Inquiry

Related Products