siRNA, Anti-SLC12A1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21265WQ-2OMe)

The product SIRGT21265WQ-2OMe is a type of small interfering RNA (siRNA) that targets SLC12A1 gene and regulates the expression of gene. The siRNA interferes with the expression of SLC12A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000338.2; NM_001184832.1
Alternative Names BSC1; NKCC2
Related Diseases Bartter-like syndromes
Purification HPLC
Target Gene
Gene ID 6557
Uniprot ID Q13621
Sub Cat Target Species Modification Scale  
SIRGT22265WQ-2F SLC12A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23265WQ-2MOE SLC12A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24265WQ-LNA SLC12A1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21265WQ-RB SLC12A1 Human Ribo-modified Inquiry
SIRGT22265WQ-BB SLC12A1 Human Backbone-modified Inquiry

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