siRNA, Anti-SMARCE1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21305WQ-2OMe)

The product SIRGT21305WQ-2OMe is a type of small interfering RNA (siRNA) that targets SMARCE1 gene and regulates the expression of gene. The siRNA interferes with the expression of SMARCE1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003079.4
Alternative Names BAF57; CSS5
Related Diseases Coffin-Siris Syndrome
Purification HPLC
Target Gene
Gene ID 6605
Uniprot ID Q969G3
Sub Cat Target Species Modification Scale  
SIRGT22305WQ-2F SMARCE1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23305WQ-2MOE SMARCE1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24305WQ-LNA SMARCE1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21305WQ-RB SMARCE1 Human Ribo-modified Inquiry
SIRGT22305WQ-BB SMARCE1 Human Backbone-modified Inquiry

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