siRNA, Anti-SMNDC1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31700WQ-2OMe)

The product SIRGT31700WQ-2OMe is a type of small interfering RNA (siRNA) that targets SMNDC1 gene and regulates the expression of gene. The siRNA interferes with the expression of SMNDC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005871.3
Alternative Names SMNR; SPF30; TDRD16C
Related Diseases Proximal Spinal Muscular Atrophy
Purification HPLC
Target Gene
Gene ID 10285
Uniprot ID O75940
Sub Cat Target Species Modification Scale  
SIRGT32700WQ-2F SMNDC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33700WQ-2MOE SMNDC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34700WQ-LNA SMNDC1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31700WQ-RB SMNDC1 Human Ribo-modified Inquiry
SIRGT32700WQ-BB SMNDC1 Human Backbone-modified Inquiry

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