siRNA, Anti-SORT1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21047WQ-2OMe)

The product SIRGT21047WQ-2OMe is a type of small interfering RNA (siRNA) that targets SORT1 gene and regulates the expression of gene. The siRNA interferes with the expression of SORT1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001205228.1; NM_002959.6
Alternative Names Gp95; LDLCQ6; NT3; NTR3
Related Diseases Myocardial Infarction
Purification HPLC
Target Gene
Gene ID 6272
Uniprot ID Q99523
Sub Cat Target Species Modification Scale  
SIRGT22047WQ-2F SORT1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23047WQ-2MOE SORT1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24047WQ-LNA SORT1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21047WQ-RB SORT1 Human Ribo-modified Inquiry
SIRGT22047WQ-BB SORT1 Human Backbone-modified Inquiry

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