siRNA, Anti-SRPRA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21414WQ-2OMe)

The product SIRGT21414WQ-2OMe is a type of small interfering RNA (siRNA) that targets SRPRA gene and regulates the expression of gene. The siRNA interferes with the expression of SRPRA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001177842.1; NM_003139.3
Alternative Names DP; SRPR; Sralpha
Related Diseases Pyrimidine Metabolic Disorder
Purification HPLC
Target Gene
Gene ID 6734
Uniprot ID P08240
Sub Cat Target Species Modification Scale  
SIRGT22414WQ-2F SRPRA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23414WQ-2MOE SRPRA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24414WQ-LNA SRPRA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21414WQ-RB SRPRA Human Ribo-modified Inquiry
SIRGT22414WQ-BB SRPRA Human Backbone-modified Inquiry

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