siRNA, Anti-STAG1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31691WQ-2OMe)

The product SIRGT31691WQ-2OMe is a type of small interfering RNA (siRNA) that targets STAG1 gene and regulates the expression of gene. The siRNA interferes with the expression of STAG1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005862.2
Alternative Names MRD47; SA1; SCC3A
Related Diseases Cornelia De Lange Syndrome
Purification HPLC
Target Gene
Gene ID 10274
Uniprot ID Q8WVM7
Sub Cat Target Species Modification Scale  
SIRGT32691WQ-2F STAG1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33691WQ-2MOE STAG1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34691WQ-LNA STAG1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31691WQ-RB STAG1 Human Ribo-modified Inquiry
SIRGT32691WQ-BB STAG1 Human Backbone-modified Inquiry

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