siRNA, Anti-SULT1E1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21450WQ-2OMe)

The product SIRGT21450WQ-2OMe is a type of small interfering RNA (siRNA) that targets SULT1E1 gene and regulates the expression of gene. The siRNA interferes with the expression of SULT1E1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005420.2
Alternative Names EST; EST-1; ST1E1; STE
Related Diseases Endometrial Cancer, Gerstmann Syndrome
Purification HPLC
Target Gene
Gene ID 6783
Uniprot ID P49888
Sub Cat Target Species Modification Scale  
SIRGT22450WQ-2F SULT1E1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23450WQ-2MOE SULT1E1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24450WQ-LNA SULT1E1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21450WQ-RB SULT1E1 Human Ribo-modified Inquiry
SIRGT22450WQ-BB SULT1E1 Human Backbone-modified Inquiry

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